Tuesday, Sept 9, 2025
6:00-9:00pm Welcome Dinner & Reception | The Hilton Embassy Hotel, Hamilton Ballroom | 231 S. Pinckney St, Madison, WI 53703
Wednesday, Sept 10, 2025
6:00am Robust Breakfast available at The Hilton Embassy Hotel | Brickstones Kitchen
8:00am Shuttle departs from The Hilton Embassy Hotel | Promega, Kornberg Building | 5430 East Cheryl Parkway, Madison
8:15-8:50 Light & Fresh Breakfast items served at Promega
8:50-9:00 Introduction, Frank Fan, Head of Biology, Research & Development, Promega Corporation
9:00-9:45 Reimagining Druggability using Chemoproteomic Platforms, Daniel K. Nomura, Ph.D.
9:45-10:10 Kinetic Scout Degraders Accelerate TPD Optimization, Fleur Ferguson, PhD, MS
10:10-10:35 Deep Proteomics Screening Enables the Discovery of Novel Molecular Glue Targets, Gisele A. Nishiguchi, PhD
10:35-10:50 Break
10:50-11:35 Informational Session on Mass Spec and its applications for TPD led by, Dr. Michael Rosenblatt & Dr. Martin Steger
11:35-11:55 Galaxy Spotlight
11:55-12:55 Lunch
12:55-1:00 Promega Product Spotlight, Amy Landreman
1:00-1:25 BRETTSA: A More Sensitive Method to Measure Target Engagement Through Protein Denaturation in Cells, James Vasta, PhD
1:25-1:50 Developing Molecular Glues for Native Protein-Protein Interactions, Michelle R. Arkin, PhD
1:50-2:05 A Lumit-Based Comparative Analysis of Degradation Dynamics Reveals Cell Context-Dependent Sensitivity to Degraders, Hicham Zegzouti, PhD
2:05-2:20 Break
2:20-2:45 Harnessing Ubiquitination to Bridge the Gap Between Degrader Binding and Function, Kristin Riching, PhD
2:45-3:10 Probing the E3 Ligase Cereblon with Small Molecules, Dr. Christina M. Woo, PhD
3:10-3:35 Induced proximity therapeutics – Cereblon and Beyond, Agnieszka Konopacka, PhD
3:35-4:00 Powering NextGen Therapeutics w/High-Throughput Proteomics:From Molecular Glues to Covalent Drug Discovery,
4:00-6:00 Vendor & Poster Show, Dinner & Networking Reception
6:00pm Shuttle from Promega to The Hilton Embassy
Thursday September 11, 2025
6:00am Robust Breakfast available at The Hilton Embassy Hotel | Brickstones Kitchen
7:45am Shuttle departs from The Hilton Embassy Hotel to Promega, Kornberg Building, 5430 East Cheryl Parkway, Madison
7:45-8:30 Light & Fresh Breakfast items served at Promega
8:30-8:35 Promega Product Spotlight, Amy Landreman
8:35-9:00 Targeting C2H2 Transcription Factors for Degradation with Molecular Glues, Dr. Radoslaw Nowak
9:00-9:25 Computational Design of Molecular Glues for Targeted Protein Degradation, Huafeng Xu, PhD
9:25-9:50 AI Next-Generation PPI Structure Prediction: Surpassing Current Limitations, Dr. Alan Nafiiev
9:50-10:00 Break
10:00-10:45 Panel Discussion: AI Driven Drug Discovery, Dr. Alan Nafiiev, Huafeng Xu, PhD, Thomas Kirkland, PhD
10:45-11:10 Investigation of Lysosome-Targeting Receptors for the Selective Degradation of Extracellular and Membrane Proteins,
11:10-11:35 Development of Novel Induced Proximity Technology for Targeted Protein Degradation and Acetylation, Md Kabir
11:35-12:00 Protein Degradation, Protein Relocalization, and Molecular Glue Discovery Technologies- Rewiring Cellular Interactomes,
12:00-12:15 How do we Monitor Degradation of Extracellular Proteins and How do Modified Bispecific Antibodies Drive Optimal
Protein Clearance? Lisa Marshall
12:15-12:20 Wrap-up, Kristin Riching
12:20p Lunch available
12:45p Shuttles depart for flights with take off times before 2:59pm
1:30p Shuttles depart for flights with take off times after 3pm