DNA and the Fight for Freedom
How Post-Conviction Testing is Changing the Justice System
Written by: Tara Luther, Promega
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Innocence is supposed to be the foundation of the American legal system—the principle that individuals are considered not guilty until proven otherwise. But for those wrongfully convicted, the burden of proving their innocence often falls squarely on their shoulders, sometimes decades after they have been sent to prison.
The advent of forensic DNA testing has revolutionized criminal investigations, but its impact on post-conviction cases has been just as profound. With the right evidence, DNA can be used to overturn wrongful convictions, revealing inconsistencies, misidentifications, and even prosecutorial misconduct. Yet, as powerful as DNA testing is, securing the opportunity to have a case reexamined remains one of the greatest challenges in the justice system.
In the webinar Murder Was the Case They Gave Me: Post-Conviction DNA Testing in a Media-Driven World, legal experts, forensic scientists, and exonerees explored the legal roadblocks, forensic advancements, and emotional toll of fighting for justice long after a conviction.
This discussion underscored a sobering truth: DNA testing is a scientific breakthrough, but exoneration requires a legal battle, one that is often as grueling as the wrongful incarceration itself.
Missed the webinar? Watch it on-demand.
The Impossible Fight: Legal Barriers to Post-Conviction DNA Testing
Defense attorney Oscar Michelen is no stranger to this fight. Having spent decades exonerating wrongfully convicted individuals, he knows firsthand that the legal system is built to uphold convictions, not revisit them.
Michelen explained how post-conviction cases operate under entirely different rules than initial trials. Once a jury has rendered a verdict, the presumption of innocence disappears, and the burden of proof shifts entirely to the defendant. In most states, a convicted individual cannot simply request DNA testing—they must convince a judge that the evidence will prove their innocence. "Judges don’t want to reopen cases," Michelen said bluntly. "The system values finality over fairness."
He outlined several key obstacles that make post-conviction relief so difficult.
Limited Access to DNA Testing
While every state has some provision for post-conviction DNA testing, the laws vary dramatically. Some states require proof that DNA testing will definitely exonerate the individual—a nearly impossible standard, since lawyers cannot predict results before testing occurs. Others set arbitrary deadlines, allowing requests only within a few years of the conviction, which often expires long before DNA advancements make testing feasible. "In many states, you have to prove your innocence before you get access to the very evidence that could prove your innocence," Michelen said. "It’s a Catch-22."
The Destruction of Evidence
One of the most devastating hurdles is that biological evidence is frequently lost or destroyed. Many crime labs and police departments discard evidence once a conviction is secured, especially in cases before DNA testing was standard practice. Without preserved evidence, exoneration through DNA becomes impossible. "In some cases, we’ve had to search old warehouses, evidence lockers, and even coroner’s offices to find samples that should have been retained," Michelen explained. "And sometimes, we find out it was thrown out long ago."
Prosecutorial Resistance
Even when DNA evidence exists, district attorneys often fight against testing. Prosecutors may argue that a conviction was already upheld on appeal, or that new testing is unnecessary because of other evidence. Some worry about the implications of reopening old cases—admitting mistakes in one case could call into question their entire record. "Innocence shouldn’t be a partisan issue, but too often, it is," Michelen said. "There’s a fear that admitting to one mistake will open the floodgates for hundreds of others."
The Cost of Freedom
Even when all legal hurdles are overcome, the financial burden of post-conviction DNA testing is often placed on the defendant or their legal team. Many exonerees spend years in prison because they simply cannot afford the testing that would prove their innocence. "This isn’t just about science," Michelen concluded. "It’s about power, resources, and whether we truly believe in justice."
"It’s impossible to explain what it feels like to hear that guilty verdict when you know you’re innocent. You want to scream, but no one will listen."
David McCallum: 29 Years Behind Bars for a Crime He Didn’t Commit
The fight for justice is not just legal—it’s deeply personal. No one knows this better than David McCallum, who was wrongfully convicted of murder at the age of 16 and spent 29 years in prison before being exonerated.
His case was based solely on a confession he made after hours of police interrogation. There was no physical evidence linking him to the crime, yet he was sentenced to life in prison.
In the webinar, McCallum shared his emotional journey—from the moment he realized he had been convicted to the decades he spent behind bars fighting to prove his innocence.
A Teenage Confession, A Lifetime Sentence
McCallum was just a teenager when he and his friend Willie Stuckey were arrested for the 1985 abduction and murder of Nathan Blenner. The two boys, overwhelmed by relentless police questioning, falsely confessed to the crime, believing that they would be allowed to go home if they cooperated.
But once their confessions were on record, there was no going back. Despite immediately recanting, both were convicted and sentenced to 25 years to life.
"It’s impossible to explain what it feels like to hear that guilty verdict when you know you’re innocent," McCallum said. "You want to scream, but no one will listen."
Decades of Fighting for Justice
McCallum’s journey to freedom was not one he walked alone. A chance connection with Ray Klonsky and his father, Ken Klonsky, would set off a chain of events that ultimately led to his exoneration. The two formed a deep friendship with McCallum, with Ray initially reaching out in 2006 as a filmmaker but quickly becoming a tireless advocate for his release. "Ray was like a brother to me," McCallum shared. "He didn’t just want to tell my story—he wanted to help me get home"
The Role of Hurricane Carter
Their fight was strengthened by none other than Rubin “Hurricane” Carter, the former middleweight boxer who had spent nearly 20 years wrongfully incarcerated before his own exoneration. Carter, who dedicated his life to freeing the innocent, saw McCallum’s case as his final mission before passing away in 2014. "He told me, ‘You will walk out of prison one day, and I want to see it happen before I die,’" McCallum recalled. "His belief in me gave me strength."
Carter’s advocacy, along with relentless legal efforts and the media attention from Fight for Justice: David & Me, ultimately pushed the Brooklyn District Attorney’s Conviction Review Unit to reinvestigate the case.
On October 15, 2014, McCallum was finally exonerated.
"I walked out, but Willie Stuckey should have been there too," McCallum said, referring to his childhood friend and co-defendant, who died in prison in 2001. "This isn’t just about me. It’s about everyone still fighting for their freedom."
The Science Behind Post-Conviction DNA Testing
Lisa Mertz and Krista Currie, both forensic DNA experts, detailed the role of forensic science in post-conviction cases. While DNA has exonerated hundreds of individuals, the process of testing decades-old evidence is far from straightforward.
Mertz and Currie outlined the key forensic challenges:
Finding the Evidence
Before any testing can begin, forensic teams must locate the original evidence. This process can take months, as records are often incomplete or missing entirely. In some cases, the only remaining DNA sample may be a degraded bloodstain or a single hair. "You have to reconstruct the history of the evidence—where it was stored, how it was handled, whether it was tested before," Mertz explained. "Every step in that chain of custody matters."
Contamination Risks
Older evidence is often stored in less-than-ideal conditions, making contamination a major concern. Forensic scientists must carefully distinguish between the original DNA and any external contaminants that may have been introduced over the years. "When we’re dealing with evidence from 20, 30, even 40 years ago, contamination is always a factor," Currie said. "We have to be meticulous in our analysis."
The Evolution of DNA Testing
DNA testing methods have advanced significantly since the 1990s. Where early techniques required large, intact samples, modern methods—such as next-generation sequencing and forensic genetic genealogy—can extract DNA from degraded or trace samples. "We can now analyze evidence that would have been considered useless 10 years ago," Mertz noted. "That’s a game-changer for post-conviction cases."
Forensic science has the potential to correct past mistakes, but only if the legal system allows it to do so.
This discussion mirrors another powerful story that will be shared at ISHI 36: that of Jeffrey Deskovic, who was wrongfully convicted of rape and murder at 16 and spent 16 years in prison before DNA evidence proved his innocence. Like McCallum, Deskovic has dedicated his life to criminal justice reform and post-conviction advocacy.
DNA may be the key to unlocking the truth, but as both McCallum’s and Deskovic’s cases show, justice requires more than science—it demands persistence, collaboration, and a willingness to confront systemic failures.
"No one should have to fight this hard for the truth," McCallum said. "But until the system changes, we will keep fighting."